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§ Encyclopedia · MODERATE (B)
B

Moderate

One adequately-powered human trial, plus supportive in-vitro / animal data. Effect plausible, not yet replicated.

# Compound Category EU Status Last reviewed
001. Cagrilintide
INN · cagrilintidum
Long-acting amylin receptor agonist · weekly subcutaneous · investigational
Metabolic NOT AUTHORISED 18 MAY 2026
002. GHK-Cu
C₁₄H₂₃CuN₆O₄ · MW 405
Copper-bound tripeptide · skin-barrier modulator, wound-healing adjunct
Cosmetic AUTHORISED 18 MAY 2026
003. Matrixyl 3000
INN · palmitoyl-tripeptide-1
Palmitoyl tripeptide-1 + tetrapeptide-7 · topical matrikine, MMP modulator
Cosmetic AUTHORISED 18 MAY 2026
004. Mazdutide
INN · mazdutidum
Dual GLP-1 / glucagon receptor agonist · weekly subcutaneous · investigational
Metabolic NOT AUTHORISED 18 MAY 2026
005. Melanotan-I
INN · afamelanotidum
Cyclic heptapeptide · selective α-MSH analogue · MC1R-preferential
Hormonal AUTHORISED 18 MAY 2026
006. Retatrutide
INN · retatrutidum
Triple GLP-1 / GIP / glucagon receptor agonist · weekly subcutaneous · investigational
Metabolic NOT AUTHORISED 18 MAY 2026
007. SS-31
INN · elamipretidum
Cell-permeable tetrapeptide · cardiolipin-binding · mitochondrial-targeted
Longevity NOT AUTHORISED 18 MAY 2026
008. Survodutide
INN · survodutidum
Dual GLP-1 / glucagon receptor agonist · weekly subcutaneous · investigational
Metabolic NOT AUTHORISED 18 MAY 2026
009. Thymosin alpha-1
INN · thymalfasinum
Acetylated 28-AA peptide · immunomodulator · enhances T-cell maturation
Recovery NOT AUTHORISED 18 MAY 2026