Editorially independent · We do not sell peptides

Pinealon

Tripeptide bioregulator · claimed pineal gland modulator and neuroprotective

EVIDENCE GRADE
D
Anecdotal
TYPE
Cognitive
EU
NOT AUTHORISED
US
NOT AUTHORISED
MOLECULAR INFORMATION

Molecular information

Length
3 amino acids
Type
Tripeptide bioregulator · claimed pineal gland modulator and neuroprotective
Amino acid sequence
Glu-Asp-Arg

Pinealon is one of the Khavinson family of “short bioregulator peptides” — a series of di-, tri- and tetrapeptides developed at the St. Petersburg Institute of Bioregulation and Gerontology. The published literature on this family is large but originates almost entirely from one group.

Claims vs evidence

  • Neuroprotection / cognitive support — preclinical only, single-group
  • Pineal-gland modulation — claimed mechanism, not independently confirmed
  • Anti-ageing / lifespan extension — extrapolated from animal studies

Why we grade it D

The same pattern as Epitalon and the other Khavinson peptides: extensive single-source literature with no independent Western replication. The underlying “bioregulator” framework — that short peptides act as tissue-specific genetic regulators — is not part of mainstream pharmacological consensus. We grade the compound family as D until independent replication appears.

Frequently asked questions

What is Pinealon?
A short tripeptide (Glu-Asp-Arg) developed by Vladimir Khavinson's St. Petersburg Institute of Bioregulation and Gerontology in the 1990s-2000s. Claimed to be a "tissue-specific bioregulator" of the pineal gland with neuroprotective and anti-ageing effects.
Is Pinealon authorised anywhere?
No — no Western regulator (EMA, FDA, MHRA) has authorised Pinealon. Sold exclusively through grey-market peptide channels, often via Russian-language vendors.
Why does Peptidepedia grade it D?
The published evidence comes almost entirely from one research group, in one country, over decades. Independent Western replication is absent. The "tissue-specific bioregulator" framework is not recognised by mainstream pharmacology.
Related compounds

Other compounds in this category