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Selank

Synthetic heptapeptide · tuftsin analogue · claimed anxiolytic + nootropic

EVIDENCE GRADE
C
Limited
TYPE
Cognitive
EU
NOT AUTHORISED
US
NOT AUTHORISED
MOLECULAR INFORMATION

Molecular information

Weight
751.9 Da
Length
7 amino acids
Type
Synthetic heptapeptide · tuftsin analogue · claimed anxiolytic + nootropic
Formula
C₃₃H₅₇N₁₁O₉
Amino acid sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro

Selank is a Russian-developed heptapeptide analogue of the endogenous immune peptide tuftsin. Authorised in Russia for generalised anxiety disorder since 2009; not authorised anywhere in the EU, UK or US. Marketed online for anxiolytic and cognitive-enhancement claims.

Claims vs evidence

  • Anxiolytic effect — Russian Phase III data, small Western pilot studies
  • Nootropic / cognitive uplift — limited preclinical support
  • Immune-modulating effects — animal-model evidence

Why we grade it C

A handful of moderate-sized Russian trials suggest a real anxiolytic signal, but the studies are not independently replicated outside their source country, and the regulatory file has not been submitted to EMA. Sold widely in grey-market peptide channels in the EU despite restricted-substance classification in NL and DE. Plausible but unproven outside its origin jurisdiction.

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