MOLECULAR INFORMATION
Molecular information
- Weight
- 711.9 Da
- Length
- 9 amino acids
- Type
- Selective ghrelin-receptor agonist (GHRP) · pulsatile GH release
- Formula
- C₃₈H₄₉N₉O₅
Amino acid sequence
Aib-His-D-2-Nal-D-Phe-Lys-NH₂ Ipamorelin is a synthetic pentapeptide GHRP (growth-hormone-releasing peptide), originally developed by Helsinn / Novo Nordisk as a candidate for GH-deficiency states. Clinical development was discontinued. Now ubiquitous in the grey-market peptide trade, often co-marketed with CJC-1295.
Claims vs evidence
- Increased lean mass / fat loss — small early-phase data, never replicated in pivotal trials
- “Side-effect-free GH boost” — preclinical selectivity claims not re-examined in modern trials
Why we grade it D
No regulatory authorisation, no completed Phase 3, no current sponsor. Sold via grey channels under stacking protocols (ipamorelin + CJC-1295) that have no published clinical support. The early Phase 2 data is decades old and never replicated.