MOLECULAR INFORMATION
Molecular information
- Type
- NNMT (nicotinamide N-methyltransferase) inhibitor · investigational metabolic modulator
5-Amino-1MQ is a research-stage NNMT inhibitor sold grey-market alongside peptides despite being a small molecule.
Claims vs evidence
- NNMT inhibition / SAM restoration — biochemistry well-characterised
- Fat-loss / metabolic improvement — rodent data only
- Body-composition change in humans — no trial
Why we grade it D
Promising preclinical mechanism, zero human evidence. Grey-market vendors price it as a fat-loss aid with no clinical support for that claim.
Frequently asked questions
- What is 5-Amino-1MQ?
- A small-molecule (technically not a peptide) inhibitor of nicotinamide N-methyltransferase (NNMT). NNMT consumes the methyl donor SAM and is elevated in obesity; inhibiting it is proposed as a strategy to increase SAM availability and metabolic flexibility.
- Is 5-Amino-1MQ a peptide?
- No — it is a small molecule. Listed here because grey-market peptide vendors stock it alongside peptides and readers expect coverage.
- Is it authorised?
- No — preclinical research compound. Mouse data showed fat-loss and metabolic improvement; no human trials registered.